The problem with MS Access is that there is no application sharing built in…and it is expensive…and it needs to be loaded on every PC. Quickbase is a completely web-based service for building tables and relatively simple applications.
Intuit (yes, the Quicken people) has done a great job on the user interface. It is robust, yet easy to use. It is also very quick. I guess intuitive and quick is what you would expect from Intuit’s Quickbase.
Finally, I have a way to collaborate with others, via the web, on data sharing needs. We are now using Quickbase for issues lists, collaborative RFP development, and project tracking. Go check it out (www.quickbase.com).
For less than $10K per year you will have an enterprise-wide application development tool that will not require IS resources.
Candid CIO 
I think that QuickBase is also an excellent tool as well! I have helped provide solutions to many companies where either budget was an issue, time was an issue or where their IT dept just didn’t have the resources. From CRM, to Project Mgmt, to Sales Force automation…and many more…
BTW…We offer the first true windows mobile platform for QuickBase!
Projjex.com is a great new site that does a fabulous job of collaboration. It’s completely browser-based, really easy to use, and has a free version. Cool videos too – I love it!
Will — we are researching quickbase. Thanks for your post. Do you find the relational elements sufficient? It seems INexpensive for what you get.